Elevate your sandwich game with the Perfect Meatloaf Sandwich—a hearty twist on comfort food that's ideal for lunch or dinner. This recipe features a tender and flavorful homemade meatloaf made with a savory blend of ground beef and pork, seasoned with garlic, onion, and Worcestershire sauce, and topped with a sweet ketchup-brown sugar glaze that caramelizes beautifully as it bakes. Layer slices of the perfectly baked meatloaf onto toasted sandwich bread spread with creamy mayonnaise, then add fresh lettuce and juicy tomato for a delightful balance of textures and flavors. This satisfying sandwich is easy to prepare and serves as the ultimate way to reinvent meatloaf leftovers into something irresistible. Perfect for busy weeknights or impressing guests, this recipe is sure to become a family favorite.
Preheat your oven to 350°F (175°C) and line a loaf pan with parchment paper or lightly grease it.
In a large mixing bowl, combine the ground beef, ground pork, breadcrumbs, milk, egg, diced onion, garlic, ketchup, Worcestershire sauce, salt, and black pepper. Mix the ingredients evenly but avoid over-mixing to keep the meatloaf tender.
Transfer the mixture to the prepared loaf pan and press it down gently to level it.
In a small bowl, mix the additional ketchup and brown sugar to make the glaze. Spread the glaze evenly over the top of the meatloaf.
Bake the meatloaf uncovered in the preheated oven for 55–60 minutes or until the internal temperature reaches 160°F (71°C).
Remove the meatloaf from the oven and let it rest for 10 minutes before slicing.
Cut 8 medium-thick slices of the bread and lightly toast them if desired.
Spread mayonnaise on one side of each slice of bread.
Place a slice of meatloaf on 4 slices of the bread, followed by a lettuce leaf and a slice or two of tomato.
Top with the remaining slices of bread, mayonnaise side down.
Cut the sandwiches in half and serve warm or at room temperature.
Calories |
3634 | ||
|---|---|---|---|
% Daily Value* |
|||
| Total Fat | 182.9 g | 234% | |
| Saturated Fat | 55.6 g | 278% | |
| Polyunsaturated Fat | 2.0 g | ||
| Cholesterol | 800 mg | 267% | |
| Sodium | 8623 mg | 375% | |
| Total Carbohydrate | 330.7 g | 120% | |
| Dietary Fiber | 16.6 g | 59% | |
| Total Sugars | 93.8 g | ||
| Protein | 186.1 g | 372% | |
| Vitamin D | 3.4 mcg | 17% | |
| Calcium | 844 mg | 65% | |
| Iron | 24.0 mg | 133% | |
| Potassium | 2812 mg | 60% | |
*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.