Transform your dinner table into a comforting Midwest-inspired feast with this Hoosier Meatloaf with Jack Daniels Sauce. Crafted with a rich blend of ground beef and pork, this classic meatloaf is infused with savory flavors from garlic, onion, and Worcestershire sauce, while a touch of ketchup adds a familiar tang. What sets this recipe apart is the irresistible Jack Daniels sauce—a sweet and smoky glaze simmered with brown sugar, tomato paste, whiskey, and a hint of mustard for a bold kick. Baked to perfection with a caramelized crust, this dish is perfect for weeknight dinners or casual gatherings. Serve it up sliced and drizzled with extra sauce for a hearty, crowd-pleasing meal that will have everyone asking for seconds. Keywords: Hoosier meatloaf, Jack Daniels sauce, Midwest comfort food, classic meatloaf recipe.
Preheat your oven to 375°F (190°C). Line a loaf pan with parchment paper or grease it lightly with oil.
Finely dice the small onion and mince the garlic cloves.
In a large mixing bowl, combine the ground beef, ground pork, breadcrumbs, milk, eggs, onion, garlic, ketchup, Worcestershire sauce, salt, and black pepper. Mix gently using your hands or a large spoon until all the ingredients are evenly combined—do not overmix.
Transfer the meat mixture into the prepared loaf pan, shaping it into a loaf. Press it down gently to ensure there are no air pockets.
Bake the meatloaf in the preheated oven for 50 minutes.
While the meatloaf is baking, make the Jack Daniels sauce. In a small saucepan over medium heat, add the brown sugar, Jack Daniels whiskey, tomato paste, apple cider vinegar, mustard, and a pinch of salt. Stir to combine.
Simmer the sauce for 5-7 minutes, stirring occasionally, until it thickens slightly. Remove it from the heat and set aside.
After the initial 50 minutes of baking, remove the meatloaf from the oven and spread half of the Jack Daniels sauce over the top. Return the meatloaf to the oven and bake for an additional 10-15 minutes, or until the internal temperature reaches 160°F (71°C).
Let the meatloaf rest for 5-10 minutes before slicing.
Serve warm with the remaining Jack Daniels sauce drizzled over the top or on the side for dipping.
Calories |
2662 | ||
|---|---|---|---|
% Daily Value* |
|||
| Total Fat | 145.8 g | 187% | |
| Saturated Fat | 55.5 g | 278% | |
| Polyunsaturated Fat | 0.1 g | ||
| Cholesterol | 888 mg | 296% | |
| Sodium | 5223 mg | 227% | |
| Total Carbohydrate | 144.9 g | 53% | |
| Dietary Fiber | 7.3 g | 26% | |
| Total Sugars | 52.8 g | ||
| Protein | 169.9 g | 340% | |
| Vitamin D | 3.4 mcg | 17% | |
| Calcium | 450 mg | 35% | |
| Iron | 18.6 mg | 103% | |
| Potassium | 2142 mg | 46% | |
*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.