Warm, hearty, and irresistibly comforting, this Melt in Your Mouth Chicken Casserole with Biscuit Topping is the ultimate family dinner recipe. Tender chunks of seared chicken combine with a creamy blend of sautéed vegetables, cheddar cheese, and savory seasonings, all blanketed by a golden, flaky biscuit topping that soaks up the rich flavors beneath. Perfect for weeknight meals or cozy gatherings, this casserole is a one-pan wonder that’s as easy to make as it is satisfying. Ready in just under an hour, it’s a delightful balance of convenience and indulgence, featuring pantry staples like cream of chicken soup, chicken broth, and canned biscuits. Serve it straight from the oven for a bubbling, golden masterpiece guaranteed to become a new household favorite.
Preheat your oven to 375°F (190°C). Grease a 9x13-inch baking dish with nonstick spray and set aside.
Season the chicken breasts with salt, pepper, and thyme. Heat the butter in a large skillet over medium heat. Sear the chicken on both sides until golden, about 4 minutes per side. Transfer to a cutting board and let rest for 5 minutes, then chop into bite-sized pieces.
In the same skillet, add the diced onion, carrots, celery, and garlic. Sauté for 5-7 minutes until softened and fragrant.
Reduce the heat to low and add the cream of chicken soup, chicken broth, and sour cream to the skillet. Stir well to combine into a creamy mixture.
Add the shredded cheddar cheese, frozen peas, and chopped chicken to the mixture. Stir until everything is well incorporated. Taste and adjust seasonings with additional salt or pepper if needed.
Pour the chicken mixture into the prepared baking dish and spread it out evenly.
Open the canned biscuits and place them on top of the chicken mixture, evenly spacing them across the surface.
Bake the casserole in the preheated oven for 25-30 minutes, or until the biscuits are golden brown and cooked through, and the filling is bubbling around the edges.
Remove from the oven and let the casserole rest for 5 minutes before serving. Serve hot and enjoy!
Calories |
3296 | ||
|---|---|---|---|
% Daily Value* |
|||
| Total Fat | 168.3 g | 216% | |
| Saturated Fat | 83.0 g | 415% | |
| Polyunsaturated Fat | 2.4 g | ||
| Cholesterol | 564 mg | 188% | |
| Sodium | 9201 mg | 400% | |
| Total Carbohydrate | 256.0 g | 93% | |
| Dietary Fiber | 23.6 g | 84% | |
| Total Sugars | 53.1 g | ||
| Protein | 186.3 g | 373% | |
| Vitamin D | 2.6 mcg | 13% | |
| Calcium | 1542 mg | 119% | |
| Iron | 18.9 mg | 105% | |
| Potassium | 3074 mg | 65% | |
*The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.